This first selection covers the United Kingdom and Australia. Recruitment status was checked on 29 October 2026 and may have changed. Research in progress is not a treatment recommendation.
United KingdomRecruiting according to original source
PrePOSE
Who experiences less pain after endometriosis surgery?
Can preoperative brain MRI and other information help predict pain outcomes?
- Where?
- Oxford, John Radcliffe Hospital, United Kingdom
- Research institution
- University of Oxford and Oxford University Hospitals
- Method
- Observational follow-up study after surgery
- Participants
- People aged 18–50 with severe stage III or IV endometriosis who are scheduled for surgery. Additional criteria include pain, English language and MRI eligibility.
What does participation involve?
Tests in Oxford before surgery and questionnaires after 3, 6 and 12 months. This is not a general offer of surgery.
When might results be available?
The registry indicates planned recruitment from December 2025 to August 2028. A publication date has not been confirmed.
Original source: University of Oxford and NIHR Be Part of Research. Checked 29 October 2026. The study site determines current eligibility and availability.
Read the original study page (opens in a new tab)United KingdomRecruiting according to original source
FENOX
What underlies endometriosis and uterine fibroids?
Researchers are investigating biological mechanisms and symptoms of endometriosis and uterine fibroids.
- Where?
- Oxford, United Kingdom
- Research institution
- University of Oxford
- Method
- Prospective cohort study with biological samples
- Participants
- Premenopausal adult women undergoing relevant gynaecological surgery; the research team determines final eligibility.
What does participation involve?
Samples and clinical information are collected around surgery and linked to symptoms and quality of life.
When might results be available?
The protocol lists March 2028 as the planned study end, not a confirmed publication date.
Original source: University of Oxford, Health Research Authority and published protocol. Checked 29 October 2026. The study site determines current eligibility and availability.
Read the original study page (opens in a new tab)AustraliaRecruiting according to original source
Sybil
Testosterone for distressingly low sexual desire before menopause
Can testosterone improve low sexual desire in premenopausal and perimenopausal women?
- Where?
- Melbourne and Sydney, Australia
- Research institution
- Monash University and Women's Health Research Institute of Australia
- Method
- Randomised double-blind placebo-controlled trial
- Participants
- Women aged 35–50 with distressing low sexual desire. Additional criteria apply.
What does participation involve?
Daily testosterone or placebo cream for six months, with up to three clinic visits in Australia.
When might results be available?
Recruitment is reported, but no confirmed publication date. Studying a treatment does not demonstrate that it works.
Original source: Monash University. Checked 29 October 2026. The study site determines current eligibility and availability.
Read the original study page (opens in a new tab)AustraliaRecruitment closed
PAMELA
Can testosterone affect muscle and bone loss after menopause?
The trial investigates whether testosterone can prevent muscle and bone loss after menopause.
- Where?
- Melbourne, Australia
- Research institution
- Monash University
- Method
- Randomised placebo-controlled trial
- Participants
- Healthy postmenopausal women aged 55–70, without hormone therapy or osteoporosis medication.
What does participation involve?
Testosterone or placebo cream for six months, assessing strength, function, hormones and bone density. No new participants are accepted according to the source.
When might results be available?
Recruitment is closed; this does not prove the trial is finished or results published. The checked source gives no publication date.
Original source: Monash University. Checked 29 October 2026. The study site determines current eligibility and availability.
Read the original study page (opens in a new tab)